McARDLE NEWS

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2016

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Elaine Alarid receives Vilas Distinguished Achievement Professorship (added 6/16)

Elaine Alarid, Ph.D., Professor of Oncology, is among 20 professors named to Vilas Distinguished Achievement Professorships.

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'Viral" Video Show HIV RNAs Bursting from Host (added 6/16)

Nathan Sherer, Ph.D., Assistant Professor of Molecular Virology and Oncology, and researchers Ginger Pocock and Jordan Becker in collaboration with Paul Ahlquist, Ph.D., Paul J. Kaesberg Professor of Molecular Virology, Oncology and Plant Pathology have leveraged some helpful technology to make HIV and its components fluoresce, revealing what their new study calls "striking, unexpected features" of retroviral activity that could lead to antiviral strategies for HIV and beyond.

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Wei Xu receives Romnes Fellowship (added 5/16)

Wei Xu, Ph.D., Professor of Oncology, is among 12 professors to receive a Romnes Faculty Fellowship.

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Paul Ahlquist receives Hilldale Award (added 3/16)

Paul Ahlquist, Ph.D., Paul J. Kaesberg Professor of Molecular Virology, Oncology and Plant Pathology; Lead Scientist for Virology, Morgridge Institute for Research; Howard Hughes Medical Institute Investigator, was named recipient of the University of Wisconsin-Madison's prestigious Hilldale Award.

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New Book Chronicles the Historic Work of McArdle Scientists Elizabeth and James Miller on the Origins and Prevention of Cancer (added 3/16)

The Understanding, Prevention and Control of Human Cancer; The Historic Work and Lives of Elizabeth Cavert Miller and James A Miller, by Robert G. McKinnell, University of Minnesota, is an account of how a married couple opened understanding of environmental carcinogenesis.

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Decades-Old Research is Basis for New Cervical Cancer Clinical Trial (added 3/16)

Research that began at the McArdle Laboratory for Cancer Research and the UW Carbone Cancer Center decades ago has led to a promising clinical trial for women in parts of the developing world, and could lead to more treatment options for cervical cancer all over the world.

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2015

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New Insight into the High Stakes Arms Race Between HMCV and Infected Cells (added 12/15)

Rob Kalejta, Ph.D., McArdle Laboratory for Cancer Research, Emily Albright, graduate student, UW-Madison, and former postdoctoral researcher, Song Hee Lee, have recently shown that individual cells in the human body have an armament designed to prevent HCMV from achieving and maintaining this latency, to shine a spotlight on the virus so the immune system knows to fight. But the virus, in turn, has developed ways to thwart these defenses.

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Understanding How Breast Cancer Resists Treatment (added 12/15)

Wei Xu, Ph.D., and Hao Zeng, graduate student, at McArdle Laboratory for Cancer Research, UW-Madison, have identified a key component of endocrine-therapy resistance in breast cancer, a finding that could lead to the development of new treatment approaches for the most common subtype of the disease.

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WELCOME - 2015 Cancer Biology Graduate Students (added 8/15)

2015 Cancer Biology Students

Pictured (left to right) Benjamin Korte, Tao Wei, Aidin Tavakoli-Tameh, Quincy Rosemarie, and Ruben Moreno.

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McArdle Laboratory Participates in Grandparents University (added 8/15)

The McArdle Laboratory, along with the University of Wisconsin-Madison Carbone Cancer Center and the Institute for Molecular Virology, hosted thirty UW-Madison alumni and their grandchildren for “Researching Cancer Cures,” a two-day major for the Grandparents University outreach event held annually and organized by the Wisconsin Alumni Association. Every summer, Grandparents University brings children ages 7 to 14 with their grandparents to learn together and experience the University’s dynamic campus atmosphere. At McArdle, participants learned how to detect cancers using tools including the polymerase chain reaction and tissue immunohistochemistry. Paul Lambert, Director of the McArdle Laboratory, introduced the session and instruction was provided by volunteer faculty, staff, post-docs and graduate students.  This was the first year that the McArdle Laboratory has participated in this exciting event..

View photos from the event here

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Petri Dish Tumor Test Could Personalize Drug Therapy for Cancer Patients (added 7/15)

Shigeki Miyamoto, Ph.D., McArdle Laboratory for Cancer Research, and David Beebe, Ph.D., Biomedical Engineering, UW-Madison, recently published news of an important advance in efforts to tailor medical treatment plans to individual patients by creating a "tumor in a dish" that can accurately anticipate a multiple myeloma patient's response to a drug.

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Dr. Bill Sugden featured speaker at Wednesday Nite @ the Lab on July 15, 2015 -- presentation available online (added 7/15)

Bill Sugden, Ph.D., presented "Understanding Burkitt's Lymphoma: From its Discovery to Working Toward its Cure" at UW-Madison's Wednesday Nite @ the Lab on Wednesday, July 15, 2015. The Wednesday Nite @ the Lab series features the latest from UW-Madison researchers as they describe their investigations and inventions that are changing how we look at life and how we lead our lives. You are encouraged to join the discussion as learners of all ages find out more and share their ideas, questions and insights.

Click here to watch online: http://www.biotech.wisc.edu/webcams?lecture=20150715_1900

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Dr. Norman Drinkwater named Associate Vice Chancellor of Biological Sciences in the Office of Research and Graduate Education (added 6/15)

Vice Chancellor for Research and Graduate Education (VCRGE) Marsha Mailick, announced the appointment of Norman Drinkwater, Ph.D., as Associate Vice Chancellor of Biological Sciences in the Office of Research and Graduate Education, effective immediately. Dr. Drinkwater has been serving in the role on an interim basis.

Click here to learn more about Dr. Drinkwater's appointment

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Dr. Christopher Bradfield named Interim WID Director (added 5/15)

On Friday, May 1, 2015, Christopher Bradfield, Ph.D., Professor of Oncology at the McArdle Laboratory for Cancer Research was appointed interim director of the Wisconsin Institute for Discovery (WID) by UW-Madison Vice Chancellor for Research and Graduate Education, Marsha Mailick.

Click here to learn more about Dr. Bradfield's appointment

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In Memoriam ~ Elizabeth Szybalski 1927-2015 (added 5/15)

Dr. Elizabeth Szybalski, long-time scientist at the McArdle Laboratory for Cancer Research, passed away on Thursday, April 23, 2015 after a long illness.  She was 87 years old.  Elizabeth was born and raised in Philadelphia, Pennsylvania, the daughter of Mabel H. Hunter and historic Orphan-Court Justice, the Honorable David G. Hunter.  She showed a strong intellect and a keen interest in science even as a young girl.  After receiving a BS degree in physics from Duke University, Elizabeth went on to earn MS and PhD degrees in microbiology at the University of Pennsylvania at a time when there were very few women in science.  Elizabeth met her future husband, Dr. Waclaw Szybalski, at Cold Spring Harbor Laboratory in 1952.  They were married in 1955.  She worked as a microbiologist at the University of Pennsylvania and in industry for several years before moving to Madison in 1960 with her husband.  For over 25 years Elizabeth and Waclaw worked together, carrying out ground-breaking research in genetics and molecular biology at the McArdle Laboratory for Cancer Research.  Her major contributions were toward creating the new field of gene therapy by performing the first-ever transfection (genetic transformation) of human cells, and developing a means of selecting for cells transfected with the human HPRT gene (encoding HPRT, also abbreviated as IMPPase) using “HAT” selection media, designed and named HAT by Elizabeth.  This became a commonplace method for introducing genes of interest into genomes of mammalian cells.  Among her other major contributions was the physical mapping of the bacterial (Escherichia coli) bio operon by electron microscopy.  Elizabeth is survived by her husband Waclaw and her children Barbara (Larry) Hunter-Sandor and Stefan Hunter Szybalski.

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Elizabeth and Waclaw Szybalski 1962.

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McArdle Alum David Reisman Wins Distinguished Professor of the Year Award (added 4/15)

Click here to learn more about David Reisman's research and the Michael J. Mungo Distinguished Professor of the Year Award.

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THANK YOU - Freedom High School Student Council Members (added 4/15)

The McArdle Laboratory for Cancer Research would like to say THANK YOU to the Freedom High School Student Council Members and others who raised $2,800 for research at the McArdle Laboratory for Cancer Research.  Each year, the Freedom High School student council hosts a formal dance to acknowledge various clubs throughout the school.  Court members fundraise and seek out donations for about a week before the dance (and the court members who raise the greatest amount reign as King and Queen!).  All proceeds are then sent to the McArdle Laboratory.

Freedom Schools chose McArdle Laboratory as the recipient of this fundraiser because they appreciate that all donations that McArdle receives go directly to cancer research.  We would like to thank everyone involved in this event for your support.  This contribution provides critical support to our efforts to identify the causes of cancer and to develop more effective approaches for preventing and treating cancer.  The research we perform in the McArdle Laboratory would not be possible without the generous support of you and many others.

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Pictured is the Freedom High School Crystal Ball Court at the dance on February 14, 2015.

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THANK YOU - Verona Area High School and Community Members - Verona, WI (added 4/15)

The McArdle Laboratory for Cancer Research would like to say THANK YOU to Verona Area School and community members who teamed up with Gray’s Tied House of Verona to sponsor their 10th Annual “Night of Hope”.  All proceeds from this event were donated to cancer research at the McArdle Laboratory in honor of all Verona Area School District families who have been affected by cancer.  This year over $5,700 was raised; over the last ten years, this fundraiser has contributed over $33,000 to the McArdle Laboratory for Cancer Research.

We would like to thank everyone involved in this event for your continued support.  A special thank you to the Verona Area School staff who organized the event, to Gray’s Tied House for hosting the event, and to everyone who donated money toward this fundraiser.  This contribution provides critical support to our efforts to identify the causes of cancer and to develop more effective approaches for preventing and treating cancer.  The research we perform in the McArdle Laboratory would not be possible without the generous support of you and many others.

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Beginning March 30, 2015 ~ McArdle Featured in Documentary on Cancer Research (added 3/15)

PBS will air a three-part documentary directed by award-winning filmmaker Barak Goodman and executive produced by Ken Burns, Cancer: The Emperor of All Maladies, based on the Pulitzer Prize-winning book. The series is described as "the most comprehensive documentary on a single disease ever made." It will be aired on Wisconsin Public Television (WPR) starting tonight, March 30, 2015 at 8:00 p.m. (You can visit the WPT site to find more information for your local station).

In conjunction with the film, WPT will also broadcast a series of lectures by UW-Madison cancer researchers. The lectures are part of WPT's "University Place" series. WPT will broadcast the following lectures and all are available are available to watch free. (Find the upcoming broadcast dates and learn how you can watch the lectures online):

  • How McArdle Scientists Found the Causes of Cancer with Oncology Professor Bill Sugden from the McArdle Laboratory for Cancer Research on Wednesday, April 1, at 4 p.m. and Monday, April 6, at 9 p.m. (in conjunction with McArdle Laboratory for Cancer Research's 75th Anniversary)
  • Cancer Research Milestones at McArdle Lab with Professor Emeritus Henry Pitot on Thursday, April 2, at 4 p.m. (in conjunction with McArdle Laboratory for Cancer Research's 75th Anniversary)
  • Diagnosing and Treating Prostate Cancer with Urology Professor David Jarrard on Friday, April 3, at 4 p.m.
  • Finding New Targets for Cancer Drugs with Professor Emeritus Dick Burgess from the McArdle Laboratory for Cancer Research on Monday, April 6, at 4:05 p.m. (in conjunction with McArdle Laboratory for Cancer Research's 75th Anniversary)
  • Mouse Models of Colon Cancer with Research Assistant Jamie Hadac on Tuesday, April 7, at 4 p.m.
  • Cancer Stem Cells Model Brain Tumor Treatments with Assistant Scientist Paul Clark from the Brain Tumor Research Laboratory on Wednesday, April 8, at 3:45 p.m.
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*NEW* - McArdle Alumni Advisory Board

The newly formed McArdle Alumni Advisory Board is comprised of about 30 alumni whom we believe represent the breadth and diversity of the >1500 graduate students and postdocs/scientists trained in McArdle over the last 75 years. Members of this advisory board all are highly successful alumni in academics, business and governmental organizations. They were active participants while at McArdle, have maintained contact with McArdle, and appreciate the positive effects of their training and time in Madison. These alumni are proud of their association with McArdle and have graciously agreed to help us improve our programs and be ambassadors for McArdle.

Click here for more information about our McArdle Alumni Advisory Board and it's members.